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Dr. Makeyouwell is a Human doctor, some of the Mr. Men and Little Misses will visit him when they have a problem
- Little Miss Trouble
- Mr. Bounce
- Little Miss Giggles
- Little Miss Busy
- Little Miss Busy Takes a Break (TV)
- Little Miss Busy D.I.Y. Teacher (TV)
- Mr. Chatterbox Loses His Voice (TV)
- A Very Happy Day For Mr. Happy (TV)
- Little Miss Greedy, Bell Of The Ball (TV)
- Mr. Grumble Boils Over (TV) (mentioned)
- Mr. Small Finds a Job (TV) (mentioned)